The best Runewords for Sorceresses are as follows:
“Call to Arms” (Amn + Ral + Mal + Ist + Ohm)
Weapon, 5 sockets, level 57
A great secondary weapon for many builds due to giving All Skills, Attack Speed, and enhancing damage.
+1 To All Skills
+40% Increased Attack Speed
+250-290% Enhanced Damage (varies)
Adds 5-30 Fire Damage
7% Life Stolen Per Hit
+2-6 To Battle Command (varies)*
+1-6 To Battle Orders (varies)*
+1-4 To Battle Cry (varies)*
Prevent Monster Heal
Replenish Life +12
30% Better Chance of Getting Magic Items
| Rune Name | Level | Lowest Act | Countess | Hellforge | Recipe |
| Amn | 25 | Act 4 Normal | Nightmare | Normal | Amn |
| Ral | 19 | Act 3 Normal | Normal | Normal | Ral |
| Mal | 49 | Act 5 Nightmare | Hell | Hell | Mal |
| Ist | 51 | Act 5 Nightmare | Hell | Hell | Ist |
| Ohm | 57 | Act 2 Hell | Hell (very rare) | – | Ohm |
“Spirit” (Tal + Thul + Ort + Ann)
Shield, 4 Sockets, Level 25
Giving all Skills, Cast Rate, and extra Resists make this a great early Runeword choice for Sorceresses.
+2 To All Skills
+25-35% Faster Cast Rate (varies)
+55% Faster Hit Recovery
+250 Defense Vs. Missile
+22 To Vitality
+89-112 To Mana (varies)
Cold Resist +35%
Lightning Resist +35%
Poison Resist +35%
+3-8 Magic Absorb (varies)
Attacker Takes Damage of 14
| Rune Name | Level | Lowest Act | Countess | Hellforge | Recipe |
| Tal | 17 | Act 1 Normal | Normal+ | Normal+ | Ral |
| Thul | 23 | Act 4 Normal | Nightmare+ | Normal | Thul |
| Ort | 21 | Act 4 Normal | Nightmare+ | Normal | Ort |
| Amn | 25 | Act 4 Normal | Nightmare+ | Normal | Amn |
“Chains of Honor” (Dol + Um + Ber + Ist)
All Skills, and various boosts to offense and defense make this a great choice for Sorceresses.
+2 To All Skills
+200% Damage To Demons
+100% Damage To Undead
8% Life Stolen Per Hit
+70% Enhanced Defense
+20 To Strength
Replenish Life +7
All Resistances +65
Damage Reduced By 8%
25% Better Chance of Getting Magic Items
| Rune Name | Level | Lowest Act | Countess | Hellforge | Recipe |
| Dol | 31 | Act 5 Normal | Nightmare | Nightmare | Dol |
| Um | 47 | Act 4 Nightmare | Hell | Nightmare | Um |
| Ber | 63 | Act 3 Hell | – | – | Ber |
| Ist | 51 | Act 5 Nightmare | Hell | Hell | Ist |
“Enigma” (Jah + Ith + Ber)
Body Armor, 3 Sockets, Level 65
One of the best late/endgame Runewords in the game, it gives All Skills, defensive boosts, and an extra point into Teleport.
+2 To All Skills
+45% Faster Run/Walk
+1 To Teleport
+750-775 Defense (varies)
(0.75 Per Character Level) +0-74 To Strength
Increase Maximum Life 5%
Damage Reduced By 8%
+14 Life After Each Kill
15% Damage Taken Goes To Mana
(1 Per Character Level) +1-99% Better Chance of Getting Magic Items
| Rune Name | Level | Lowest Act | Countess | Hellforge | Recipe |
| Jah | 65 | Act 4 Hell | – | – | Jah |
| Ith | 15 | Act 1 Normal | Normal+ | Normal | Ith |
| Ber | 63 | Act 3 Hell | – | – | Ber |
“Heart of the Oak” (Ko + Vex + Pul + Thul)
Mace, 4 Sockets, Level 55
A huge boost to skills and cast rate, some mana buffs, and even some charged summons makes this Runeword a great choice for the Sorceress.
+3 To All Skills
+40% Faster Cast Rate
+75% Damage To Demons
+100 To Attack Rating Against Demons
Adds 3-14 Cold Damage, 3 sec. Duration (Normal)
7% Mana Stolen Per Hit
+10 To Dexterity
Replenish Life +20
Increase Maximum Mana 15%
All Resistances +30-40 (varies)
Level 4 Oak Sage (25 Charges)
Level 14 Raven (60 Charges)